Pain Relief After Instrumented Spinal surgEry (PRAISE) trial

https://www.sheffield.ac.uk/ctru/current-trials/praise

An NIHR HTA funded randomised controlled trial and economic evaluation investigating the clinical and cost effectiveness of three approaches to postoperative pain relief following elective posterior lumbar instrumented fusion (+/- decompression) at 1-3 levels:

• Usual care 
• Usual care + Intrathecal Opioids 
• Usual care + Erector Spinae plane Block

The primary outcome is back pain on movement around the bed (sitting up and/or turning) on a 0-100 VAS at 24 hours post-surgery.

We are currently recruiting participants and setting up new sites. The Sponsor is Sheffield Teaching Hospitals NHS Foundation Trust.

For more information or to express your interest in setting up as a recruiting site, please contact:

Sienna Hamer-Kiwacz (s.a.hamer-kiwacz@sheffield.ac.uk) – Trial Manager

Prof Matthew Wilson(m.j.wilson@sheffield.ac.uk) – Chief Investigator/Featherstone Professor of Anaesthesia

Mr Ashley Cole (Ashley.cole4@nhs.net) – Co-Chief Investigator/Consultant Spinal Surgeon